Prediction of PPAR- ligand-mediated physiological changes using gene expression profiles
نویسندگان
چکیده
منابع مشابه
Prediction of PPAR-alpha ligand-mediated physiological changes using gene expression profiles.
Peroxisome proliferator-activated receptor (PPAR)-alpha controls the transcription of a variety of genes involved in lipid metabolism and is the target receptor for the hypolipidemic drug class of fibrates. In the present study, the molecular and physiological effects of seven different PPAR-activating drugs have been examined in a rodent model of dyslipidemia. The drugs examined were selected ...
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ژورنال
عنوان ژورنال: The Journal of Lipid Research
سال: 2003
ISSN: 0022-2275
DOI: 10.1194/jlr.d300239-jlr200